The regulations of this chapter apply to all California Institute for Regenerative Medicine (“CIRM”) Grants issued to For-Profit Organizations on or after the effective date of these regulations. By accepting a CIRM Grant, the Grantee agrees to comply with these regulations. Any new or amended regulations subsequently adopted by the Independent Citizens Oversight Committee (“ICOC”) will apply to Currently Active Grants on the start date of the next noncompetitive renewal period after the effective date of the regulations, except amendments to Title 17, California Code of Regulations, sections 100406, 100407 and 100408, which shall only apply to grants awarded after adoption of the new or amended regulations. CIRM will notify a Grantee's Principal Investigator and Authorized Organizational Official of the adoption of new or amended regulations. In addition, all revisions to CIRM regulations will be posted on the CIRM website at www.cirm.ca.gov. Failure of actual notice to a Grantee's Principal Investigator or Authorized Organizational Official shall not excuse non-compliance with any regulation if CIRM has notified the Grantee of the changes.