A. Applications may be made only when the wind is not blowing in the direction of desirable vegetation, waterways, or where human health or the environment may be adversely impacted. Where desirable vegetation, waterways, or human health and the environment cannot be protected by ensuring they are not downwind from the application site then, unless a greater distance is required by the label or other applicable State or Federal rules, a 300 foot minimum buffer zone must be maintained between the protected entity (desirable vegetation, waterway, etc.) and the sprayed area.